4.8 stars from 1,000+ reviews

The World's First Hydroxyapatite Oral Spray.

Tooth decay (caries) affects 2.5 billion people worldwide — and your mouth’s acidic pH is the reason. Our dentist-developed formula helps replenish essential minerals at the molecular level and supports optimal oral pH balance — giving you protection anytime, anywhere.

GET CARISPRAY

✓ Dentist formulated

✓ Patent-Pending Technology

✓ Clinically-Proven

✓ Completely safe

84% Less Staining

74% Less Tartar Formation

82% Whiter and Brighter Teeth

100% Ease of Use

84% Less Staining

74% Less Tartar Formation

82% Whiter and Brighter Teeth

100% Ease of Use

84% Less Staining

74% Less Tartar Formation

82% Whiter and Brighter Teeth

100% Ease of Use

84% Less Staining

74% Less Tartar Formation

82% Whiter and Brighter Teeth

100% Ease of Use

84% Less Staining

74% Less Tartar Formation

82% Whiter and Brighter Teeth

100% Ease of Use

84% Less Staining

74% Less Tartar Formation

82% Whiter and Brighter Teeth

100% Ease of Use

84% Less Staining

74% Less Tartar Formation

82% Whiter and Brighter Teeth

100% Ease of Use

84% Less Staining

74% Less Tartar Formation

82% Whiter and Brighter Teeth

100% Ease of Use

84% Less Staining

74% Less Tartar Formation

82% Whiter and Brighter Teeth

100% Ease of Use

84% Less Staining

74% Less Tartar Formation

82% Whiter and Brighter Teeth

100% Ease of Use

TRANSFORM YOUR ORAL HEALTH

Clinically proven, patent-pending technology with nano-hydroxyapatite remineralization helps protect against cavities before they start.

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Restores Natural Whiteness

Revives your smile’s natural shine without harsh abrasives.

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Smooth and Relief

Gently soothes irritation and keeps teeth feeling silky smooth.

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Advanced Cavity Protection

Helps prevent cavities and keeps young teeth strong.

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Sensitivity Support

Calms sensitive teeth while reinforcing enamel defenses.

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Enamel Remineralization

Strengthens and rebuilds tooth enamel for lasting protection.

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Smooths & Protects

Creates a protective barrier to prevent future damage and decay

CariSpray scientifically-backed formula contains:

  • Nano-Hydroxyapatite: The same mineral that makes up 97% of your tooth enamel. It remineralizes and strengthens teeth at the molecular level, using particles identical in size to those in natural teeth and bones—and in a concentration precisely matched to replace your teeth’s daily mineral loss.
  • Xylitol (25%): Clinically shown to support a balanced oral microbiome and help maintain a healthy mouth environment.
  • pH+ Buffering System: Sodium Bicarbonate and Potassium compounds that instantly balance mouth acidity.

In a 30-day study, men and women using CariSpray reported:

0%

Less Staining

0%

Less Tartar Formation

0%

Reported Whiter and Brighter Teeth

0%

Found It Easy to Use

How Carispray Works?

  • 1. pH Homeostasis Restoration

    The formulation quickly rebalances oral pH from acidic levels (≤5.5) to a more protective, alkaline state (≥7.0), creating the ideal environment for strong, healthy-looking enamel.

  • 2.Targeted Oral Balance

    Bacteria interact with xylitol thinking it’s sugar, but they cannot process it. This metabolic interaction supports a balanced oral environment, helping the mouth feel cleaner and fresher.

  • 3. Biomimetic Remineralization

    Precision-sized nano-hydroxyapatite crystals (20–80 nanometers) bond to the tooth surface, helping smooth, strengthen, and enhance the appearance of enamel by supporting its natural mineral balance.

    Pharmaceutical-Grade Clinical Validation & Purity Certification

    CARISPRAY Adults has undergone rigorous validation through accredited European laboratories following pharmaceutical manufacturing protocols. The formulation received comprehensive analytical verification through ISO-certified testing facilities, establishing clinical-grade purity and biocompatibility standards.

     

    Advanced Clinical Validation Protocol:

    • Sterile Microbiological Validation
    • Antimicrobial Preservation Efficacy
    • Dermatological Biocompatibility
    • European Pharmaceutical Compliance

    All procedures conducted under cGMP conditions by accredited laboratories, including Meyer d.o.o., Dr Koziej Clinical Research Institute, and Croatian National Institute of Public Health.

    Join 1,000+ People Who've Made the Switch to Smarter Oral Care

    Professional-grade oral spray that balances oral pH and protects against cavities —backed by real results and a 30-day guarantee.

    CariSpray nano-hydroxyapatite oral spray benefits
    CariSpray nano-hydroxyapatite oral spray benefits
    CariSpray Nano-Hydroxyapatite Oral Spray BOGO
    CariSpray Nano-Hydroxyapatite Oral Spray BOGO
    CariSpray Nano-Hydroxyapatite Oral Spray BOGO

    ⭐⭐⭐⭐⭐ 4.8 / 2,000+ users

    Finally — Cavity Protection That Works Between Brushings, After Meals, and While You Sleep

    Developed by Dr. Martincevic, just two sprays help rebuild what daily life strips away — protecting your enamel around the clock, even after acidic foods, missed brushings, and long workdays.
    CLINICAL DATA +

    In a 30-day study, men and women using CariSpray reported:

    ✓ 84%     less staining

    ✓ 73% less tartar buildup

    ✓ 82% of users said their teeth looked whiter and brighter

    ✓ 100%     found it easy to use


    LABORATORY FINDINGS:

    • 62% improved cavity protection within just 3 minutes

    FLUIDINOVA Independent n-HA Research:

    • Complete dentin tubule sealing within 7 days

    • Sustained remineralization even after acid exposure

    • Electron microscopy confirms nano-hydroxyapatite particle integration into the enamel microstructure.

    FEATURES +

    Created by implantologist Dr. Martincevic to solve cavity problems in children—now available to everyone.

    Science-Driven Innovation
    We don't follow trends—we follow research. Every formula is built on clinical evidence and real-world results.

    CariSpray maintains optimal pH levels for healthy teeth and gums. No sugar, dyes, or harsh alcohol.

    🔬 Teeth Remineralization

    Nano-hydroxyapatite penetrates enamel to rebuild tooth structure from within—strengthening teeth at the molecular level with every use.

    ✨ Restores Natural Whiteness

    Nano-hydroxyapatite fills microscopic imperfections in enamel, smoothing the tooth surface to naturally reflect light and reveal your teeth's inherent brightness—without harsh bleaching agents.

    🛡️ Protects Tooth Surface

    Creates a protective mineral layer that shields enamel from daily acid exposure, wear, and environmental damage—strengthening your teeth's natural defenses with every spray.

    🦷 Sensitivity Support

    Helps seal exposed dentin tubules that cause sensitivity, providing gentle relief from hot, cold, and sweet triggers while supporting long-term enamel health.

    WHAT WE BELIEVE +

    We believe you shouldn’t keep getting cavities despite doing everything right. Brushing twice a day shouldn’t be the bare minimum — it should be enough. Modern diets and traditional oral care leave gaps — the hours between brushing, the pH swings from coffee, snacks, and stress, and the damage that happens while you sleep. That’s why we created CariSpray: professional-grade protection that works between the gaps. Real prevention that fits real life — whenever and wherever you need it.

    INGRIDIENTS +

    PROFESSIONAL-GRADE FORMULA

    Active Ingredients

    CariSpray scientifically-backed formula contains:

    • Nano-Hydroxyapatite:
      The same mineral that makes up 97% of your tooth enamel. It remineralizes and strengthens teeth at the molecular level, using particles identical in size to those in natural teeth and bones—and in a concentration precisely matched to replace your teeth’s daily mineral loss.
    • Xylitol (25%): Clinically shown to support a balanced oral microbiome and help maintain a healthy mouth environment.
    • pH+ Buffering System: Sodium Bicarbonate and Potassium compounds that instantly balance
      mouth acidity.

    Supporting Ingredients

    Our gentle, alcohol-free base includes: Water (Aqua), Glycerin, Polysorbate 20, Potassium Citrate, Potassium Chloride, Sodium Benzoate, Potassium Sorbate, natural flavor essences (Menthol, Citric Acid, Anethole, Beta-Caryophyllene), and citrus essential oils for fresh taste.

    Usage Instructions

    WHEN TO USE: After meals, snacks, coffee, before bedtime, or anytime you want stronger teeth and fresher breath.

    What's NOT Inside

    CariSpray is alcohol-free, fluoride-free, and contains no harsh chemicals, artificial dyes, or synthetic preservatives.

    WHY CARISPRAY +

    The science you've been missing!

    1. Clinically Studied Formula: Oral care innovation that supports natural oral health. CariSpray's patent-pending technology and nano-hydroxyapatite help maintain optimal oral pH balance—supporting your daily oral care routine at home.

    2. Professional-Grade Formula: The same technology dentists use, now in your pocket. Alcohol-free, gentle formula that doesn't burn or sting, yet delivers measurable pH balance immediately.

    3. Instant & Portable: Designed for real life. Whether you're teaching, presenting, or simply between meals—just spray and go. Perfect discretion when you need it most.

    4. No More Dental Anxiety: End the cycle of painful procedures and expensive treatments. See your mouth's pH transform in real-time. No guesswork, just pure protection.

    CERTIFICATIONS +

    Manufactured in FDA-registered, family-safe facilities with specialized quality controls.

    HOW TO USE +

    SHAKE • SPRAY • PROTECT

    1.    SHAKE 5 times

    2.    SPRAY 2-3 pumps on teeth or under
    tongue

    3.    SWISH 30 seconds

    4.    DO NOT RINSE, let the ingredients stay
    on the teeth for maximum benefit

    WHEN TO USE: After meals, snacks,
    coffee, before bedtime, or anytime you want stronger teeth.

    Real Customers Who Avoided Expensive Dental Work


    See how CariSpray's pH-balancing technology helped these customers prevent costly dental procedures and regain confidence in their oral health.

    • Finally broke my cavity cycle after 30 years

      I’ve battled cavities for years despite perfect brushing. My dentist blamed low pH, so I tried this spray—6 weeks later, my pH normalized and for the first time in decades, I heard “no cavities”!

      Sara K.

    • Avoided my worst fear — more dental work

      I’ve had dental anxiety since a painful root canal, but using this daily gave me control again. My last visit was just a cleaning—no drilling, no bad news. For once, I’m not dreading the dentist!

      Marko D.

    • A product backed by real science

      Getting my autistic son to cooperate with tooth brushing was impossible. This spray is so gentle and tastes good enough that he actually opens his mouth for it.

      Dr. Ema R.

      CariSpray comparison showing superior cavity protection

      US VS. THEM COMPARISON

      Not another harsh mouthwash or temporary fix. Just dentist-developed pH science that actually protect against cavities.

      Hey, I'm Dr. Toni – a dentist, founder of OralAdvance Labs and creator of CariSpray

      The moment that changed everything happened during a routine checkup. A 6-year-old named Luna needed her third filling in just one year. As I prepped the drill, her mom's voice cracked: "Doctor, I don't understand. We brush morning and night with fluoride toothpaste. We cut back on snacks and juice. I even bought those expensive kids' vitamins. What else can I possibly do?"

      Read Our Story

      FAQ

      CariSpray is the world’s first nano-hydroxyapatite oral spray, creating an entirely new category of oral care. It works through a triple mechanism: restoring pH balance, promoting microbiome optimization via xylitol, and enabling molecular-level tooth remineralization.

      Yes. CariSpray is completely safe to swallow.

      The enamel on your teeth is composed of approximately 97% hydroxyapatite, and CariSpray’s 0.45% nano-hydroxyapatite concentration is carefully designed to replace the minerals your teeth naturally lose each day from dietary acids.

      Since these are biocompatible minerals already found in your body, swallowing the product poses no risk. No rinsing is necessary.

      OralAdvance partners with FLUIDINOVA,
      Europe’s leading manufacturer of high purity, research-grade nano hydroxyapatite.

      Key material specifications: Sub-100 nm rod-shaped particles 98% dentin tubule occlusion (vs. 82% for competitors) RDA <10 (extremely low abrasivity).

      Pharmaceutical-grade purity.

      We use the only nano-hydroxyapatite approved by the EU's Scientific Committee on Consumer Safety as entirely safe, biocompatible, and non-toxic.

      Yes – both clinical and laboratory studies confirm its effectiveness.

      30-Day Use Study Results:

      ✓ 84% less staining

      ✓ 73% less tartar buildup

      ✓ 82% of users said their teeth looked whiter and brighter

      ✓ 100% found it easy to use

      Laboratory Findings:

      • 62% improved cavity protection within just 3 minutes

      FLUIDINOVA Independent n-HA Research:

      • Complete dentin tubule sealing within 7 days

      • Sustained remineralization even after acid exposure

      • Electron microscopy confirms nano-hydroxyapatite particle integration into
      the enamel microstructure

      Research shows that up to 10–14% of enamel hydroxyapatite can be lost during cavity development in typical caries models lasting 15–30 days. This translates to an average daily mineral loss of approximately 0.67–0.93%.

      The 0.46% n-HA concentration in CariSpray is precisely formulated to replace this daily loss and maintain optimal mineral balance.

      Results occur at multiple levels: Immediate: Fresh breath and cleaner mouthfeel.

      Within days: Improved oral pH balance

      After 2–4 weeks: Noticeable enamel smoothness and reduced sensitivity

      Long-term: Sustained remineralization and caries protection

      Clinical data show measurable results
      within days: Immediate: Fresh breath and cleaner mouth sensation

      1 week: 35% reduction in tooth sensitivity

      2–4 weeks: Up to 80% reduction in sensitivity

      6 months: Up to 62% reduction in long-term hypersensitivity

      As validated in FLUIDINOVA’s independent
      research.

      Official CariSpray EU Store


      CariSpray EU offers cavity-protection oral sprays designed for everyday oral care. Our formulas use cosmetic-grade ingredients and enamel-supporting minerals to help keep your mouth feeling clean and fresh throughout the day.
      We provide fast shipping across Europe and dedicated support for families, adults, and professionals. Discover a simpler way to support daily oral hygiene with CariSpray.

      Explore our Kids Spray
      Shop CariSpray Adult