The World's First Hydroxyapatite Oral Spray.
Strengthens enamel and supports cavity protection — proven to reduce Streptococcus mutans by 62% in vitro in just 3 minutes.
Tooth decay (caries) affects 2.5 billion people worldwide — and your mouth’s acidic pH is the reason. Our dentist-developed formula helps replenish essential minerals at the molecular level and supports optimal oral pH balance — giving you protection anytime, anywhere.
Dentist formulated
Patent-Pending Technology
Clinically-Proven
Completely safe
84% Less Staining
74% Less Tartar Formation
82% Whiter and Brighter Teeth
100% Ease of Use
84% Less Staining
74% Less Tartar Formation
82% Whiter and Brighter Teeth
100% Ease of Use
84% Less Staining
74% Less Tartar Formation
82% Whiter and Brighter Teeth
100% Ease of Use
84% Less Staining
74% Less Tartar Formation
82% Whiter and Brighter Teeth
100% Ease of Use
84% Less Staining
74% Less Tartar Formation
82% Whiter and Brighter Teeth
100% Ease of Use
84% Less Staining
74% Less Tartar Formation
82% Whiter and Brighter Teeth
100% Ease of Use
84% Less Staining
74% Less Tartar Formation
82% Whiter and Brighter Teeth
100% Ease of Use
84% Less Staining
74% Less Tartar Formation
82% Whiter and Brighter Teeth
100% Ease of Use
84% Less Staining
74% Less Tartar Formation
82% Whiter and Brighter Teeth
100% Ease of Use
84% Less Staining
74% Less Tartar Formation
82% Whiter and Brighter Teeth
100% Ease of Use
TRANSFORM YOUR ORAL HEALTH
Clinically proven, patent-pending technology with nano-hydroxyapatite remineralization helps protect against cavities before they start.
Restores Natural Whiteness
Revives your smile’s natural shine without harsh abrasives.
Smooth and Relief
Gently soothes irritation and keeps teeth feeling silky smooth.
Advanced Cavity Protection
Helps prevent cavities and keeps young teeth strong.
Sensitivity Support
Calms sensitive teeth while reinforcing enamel defenses.
Enamel Remineralization
Strengthens and rebuilds tooth enamel for lasting protection.
Smooths & Protects
Creates a protective barrier to prevent future damage and decay
CariSpray scientifically-backed formula contains:
- Nano-Hydroxyapatite: The same mineral that makes up 97% of your tooth enamel. It remineralizes and strengthens teeth at the molecular level, using particles identical in size to those in natural teeth and bones—and in a concentration precisely matched to replace your teeth’s daily mineral loss.
- Xylitol (25%): Clinically shown to support a balanced oral microbiome and help maintain a healthy mouth environment.
- pH+ Buffering System: Sodium Bicarbonate and Potassium compounds that instantly balance mouth acidity.
Clinically proven, patent-pending technology with nano-hydroxyapatite remineralization helps protect against cavities before they start.
In a 30-day study, men and women using CariSpray reported:
0%
Less Staining
0%
Less Tartar Formation
0%
Reported Whiter and Brighter Teeth
0%
Found It Easy to Use
How Carispray Works?
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1. pH Homeostasis Restoration
The formulation quickly rebalances oral pH from acidic levels (≤5.5) to a more protective, alkaline state (≥7.0), creating the ideal environment for strong, healthy-looking enamel.
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2.Targeted Oral Balance
Bacteria interact with xylitol thinking it’s sugar, but they cannot process it. This metabolic interaction supports a balanced oral environment, helping the mouth feel cleaner and fresher.
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3. Biomimetic Remineralization
Precision-sized nano-hydroxyapatite crystals (20–80 nanometers) bond to the tooth surface, helping smooth, strengthen, and enhance the appearance of enamel by supporting its natural mineral balance.
Pharmaceutical-Grade Clinical Validation & Purity Certification
CARISPRAY Adults has undergone rigorous validation through accredited European laboratories following pharmaceutical manufacturing protocols. The formulation received comprehensive analytical verification through ISO-certified testing facilities, establishing clinical-grade purity and biocompatibility standards.
Advanced Clinical Validation Protocol:
- Sterile Microbiological Validation
- Antimicrobial Preservation Efficacy
- Dermatological Biocompatibility
- European Pharmaceutical Compliance
All procedures conducted under cGMP conditions by accredited laboratories, including Meyer d.o.o., Dr Koziej Clinical Research Institute, and Croatian National Institute of Public Health.
Join 10,000+ People Who've Made the Switch to Smarter Oral Care
Professional-grade oral spray that balances oral pH and protects against cavities —backed by real results and a 30-day guarantee.
⭐⭐⭐⭐⭐ 4.8 / 1,000+ reviews
The pH-Balanced Cavity Protection Spray with Hydroxyapatite
The Ultimate Protection for the 1 in 3 adults who still get cavities despite doing everything right.
Developed by Dr. Martincevic , our comprehensive triple-action formula actively supports an optimal oral pH balance and visibly aids natural enamel renewal with Nano-Hydroxyapatite. It is further enhanced with 25% Xylitol to support a balanced oral microbiome.
CariSpray Nano-Hydroxyapatite Oral Spray
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CLINICAL DATA
CLINICAL DATA
In a 30-day study, men and women using CariSpray reported:
✓ 84% less staining
✓ 73% less tartar buildup
✓ 82% of users said their teeth looked whiter and brighter
✓ 100% found it easy to use
LABORATORY FINDINGS:
• 62% improved cavity protection within just 3 minutes
FLUIDINOVA Independent n-HA Research:
• Complete dentin tubule sealing within 7 days
• Sustained remineralization even after acid exposure
• Electron microscopy confirms nano-hydroxyapatite particle integration into the enamel microstructure.
FEATURES
FEATURES
Created by implantologist Dr. Martincevic to solve cavity problems in children—now available to everyone.
Science-Driven Innovation
We don't follow trends—we follow research. Every formula is built on clinical evidence and real-world results.
CariSpray maintains optimal pH levels for healthy teeth and gums. No sugar, dyes, or harsh alcohol.
🔬 Teeth Remineralization
Nano-hydroxyapatite penetrates enamel to rebuild tooth structure from within—strengthening teeth at the molecular level with every use.
✨ Restores Natural Whiteness
Nano-hydroxyapatite fills microscopic imperfections in enamel, smoothing the tooth surface to naturally reflect light and reveal your teeth's inherent brightness—without harsh bleaching agents.
🛡️ Protects Tooth Surface
Creates a protective mineral layer that shields enamel from daily acid exposure, wear, and environmental damage—strengthening your teeth's natural defenses with every spray.
🦷 Sensitivity Support
Helps seal exposed dentin tubules that cause sensitivity, providing gentle relief from hot, cold, and sweet triggers while supporting long-term enamel health.
WHAT WE BELIEVE
WHAT WE BELIEVE
We believe you shouldn’t keep getting cavities despite doing everything right. Brushing twice a day shouldn’t be the bare minimum — it should be enough. Modern diets and traditional oral care leave gaps — the hours between brushing, the pH swings from coffee, snacks, and stress, and the damage that happens while you sleep. That’s why we created CariSpray: professional-grade protection that works between the gaps. Real prevention that fits real life — whenever and wherever you need it.
INGRIDIENTS
INGRIDIENTS
PROFESSIONAL-GRADE FORMULA
Active Ingredients
CariSpray scientifically-backed formula contains:
- Nano-Hydroxyapatite:
The same mineral that makes up 97% of your tooth enamel. It remineralizes and strengthens teeth at the molecular level, using particles identical in size to those in natural teeth and bones—and in a concentration precisely matched to replace your teeth’s daily mineral loss. - Xylitol (25%): Clinically shown to support a balanced oral microbiome and help maintain a healthy mouth environment.
- pH+ Buffering System: Sodium Bicarbonate and Potassium compounds that instantly balance
mouth acidity.
Supporting Ingredients
Our gentle, alcohol-free base includes: Water (Aqua), Glycerin, Polysorbate 20, Potassium Citrate, Potassium Chloride, Sodium Benzoate, Potassium Sorbate, natural flavor essences (Menthol, Citric Acid, Anethole, Beta-Caryophyllene), and citrus essential oils for fresh taste.
Usage Instructions
WHEN TO USE: After meals, snacks, coffee, before bedtime, or anytime you want stronger teeth and fresher breath.
What's NOT Inside
CariSpray is alcohol-free, fluoride-free, and contains no harsh chemicals, artificial dyes, or synthetic preservatives.
WHY CARISPRAY
WHY CARISPRAY
The science you've been missing!
1. Clinically Studied Formula: Oral care innovation that supports natural oral health. CariSpray's patent-pending technology and nano-hydroxyapatite help maintain optimal oral pH balance—supporting your daily oral care routine at home.
2. Professional-Grade Formula: The same technology dentists use, now in your pocket. Alcohol-free, gentle formula that doesn't burn or sting, yet delivers measurable pH balance immediately.
3. Instant & Portable: Designed for real life. Whether you're teaching, presenting, or simply between meals—just spray and go. Perfect discretion when you need it most.
4. No More Dental Anxiety: End the cycle of painful procedures and expensive treatments. See your mouth's pH transform in real-time. No guesswork, just pure protection.
CERTIFICATIONS
CERTIFICATIONS
Manufactured in FDA-registered, family-safe facilities with specialized quality controls.
HOW TO USE
HOW TO USE
SHAKE • SPRAY • PROTECT
1. SHAKE 5 times
2. SPRAY 2-3 pumps on teeth or under
tongue
3. SWISH 30 seconds
4. DO NOT RINSE, let the ingredients stay
on the teeth for maximum benefit
WHEN TO USE: After meals, snacks,
coffee, before bedtime, or anytime you want stronger teeth.
-
“I started using CariSpray twice a day, and within a week my teeth felt smoother and cleaner. It’s so convenient after meals — no rinsing, no hassle, just lasting freshness.”
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“As someone who drinks coffee daily, this spray has been a game changer. My enamel feels stronger, and my dentist even noticed less staining at my last visit.”
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“CariSpray fits perfectly into my busy routine. It keeps my mouth fresh and my teeth feeling stronger — a smart upgrade from regular mouthwash.”
Real Customers Who Avoided Expensive Dental Work
See how CariSpray's pH-balancing technology helped these customers prevent costly dental procedures and regain confidence in their oral health.
US VS. THEM COMPARISON
Not another harsh mouthwash or temporary fix. Just dentist-developed pH science that actually protect against cavities.
Hey, I'm Dr. Toni – a dentist, founder of OralAdvance Labs and creator of CariSpray
The moment that changed everything happened during a routine checkup. A 6-year-old named Luna needed her third filling in just one year. As I prepped the drill, her mom's voice cracked: "Doctor, I don't understand. We brush morning and night with fluoride toothpaste. We cut back on snacks and juice. I even bought those expensive kids' vitamins. What else can I possibly do?"
FAQ
What is CariSpray?
What is CariSpray?
CariSpray is the world’s first nano-hydroxyapatite oral spray, creating an entirely new category of oral care. It works through a triple mechanism: restoring pH balance, promoting microbiome optimization via xylitol, and enabling molecular-level tooth remineralization.
Is it safe to swallow?
Is it safe to swallow?
Yes. CariSpray is completely safe to swallow.
The enamel on your teeth is composed of approximately 97% hydroxyapatite, and CariSpray’s 0.45% nano-hydroxyapatite concentration is carefully designed to replace the minerals your teeth naturally lose each day from dietary acids.
Since these are biocompatible minerals already found in your body, swallowing the product poses no risk. No rinsing is necessary.
Where do you source your nano-hydroxyapatite?
Where do you source your nano-hydroxyapatite?
OralAdvance partners with FLUIDINOVA,
Europe’s leading manufacturer of high purity, research-grade nano hydroxyapatite.
Key material specifications: Sub-100 nm rod-shaped particles 98% dentin tubule occlusion (vs. 82% for competitors) RDA <10 (extremely low abrasivity).
Pharmaceutical-grade purity.
What type of nano-hydroxyapatite do you use?
What type of nano-hydroxyapatite do you use?
We use the only nano-hydroxyapatite approved by the EU's Scientific Committee on Consumer Safety as entirely safe, biocompatible, and non-toxic.
Does CariSpray actually work?
Does CariSpray actually work?
Yes – both clinical and laboratory studies confirm its effectiveness.
30-Day Use Study Results:
✓ 84% less staining
✓ 73% less tartar buildup
✓ 82% of users said their teeth looked whiter and brighter
✓ 100% found it easy to use
Laboratory Findings:
• 62% improved cavity protection within just 3 minutes
FLUIDINOVA Independent n-HA Research:
• Complete dentin tubule sealing within 7 days
• Sustained remineralization even after acid exposure
• Electron microscopy confirms nano-hydroxyapatite particle integration into
the enamel microstructure
Why choose 0.46% nano-hydroxyapatite?
Why choose 0.46% nano-hydroxyapatite?
Research shows that up to 10–14% of enamel hydroxyapatite can be lost during cavity development in typical caries models lasting 15–30 days. This translates to an average daily mineral loss of approximately 0.67–0.93%.
The 0.46% n-HA concentration in CariSpray is precisely formulated to replace this daily loss and maintain optimal mineral balance.
How long before I see results?
How long before I see results?
Results occur at multiple levels: Immediate: Fresh breath and cleaner mouthfeel.
Within days: Improved oral pH balance
After 2–4 weeks: Noticeable enamel smoothness and reduced sensitivity
Long-term: Sustained remineralization and caries protection
How quickly does CariSpray work for sensitive teeth?
How quickly does CariSpray work for sensitive teeth?
Clinical data show measurable results
within days: Immediate: Fresh breath and cleaner mouth sensation
1 week: 35% reduction in tooth sensitivity
2–4 weeks: Up to 80% reduction in sensitivity
6 months: Up to 62% reduction in long-term hypersensitivity
As validated in FLUIDINOVA’s independent
research.